Wir verwenden Cookies, um Ihren Besuch auf unserer Webseite effizienter zu machen und Ihnen mehr Benutzerfreundlichkeit bieten zu können. Informationen darüber, wie wir Cookies verwenden oder wie man sie blockieren kann, finden Sie in unserer Cookie-Richtlinie.

Cell Migration/Invasion

Cell Migration/InvasionCell migration and invasion are live cell kinetic assays useful in oncology research. The principle difference between migration and invasion is that migration refers to normal cell movement; whereas invasion describes cells actively invading surrounding tissue. It can do this under the influence of a chemoattractant gradient and secretion of proteases. There are numerous methods for performing these assays including scratch assays performed on a monolayer of cells adhered to plasticware (microplates or culture inserts) or using 3D cell culture models. BioTek’s Scratch Assay Starter Kit automates the creation of reproducible scratch wounds in 96- and 24-well plates; its Scratch Assay App has a simplified interface for kinetic image capture and analysis that can be used to quantify migration such as wound width, % confluence and healing rate (max V).  Gen5 software enables quantification of invadopodia area for tumor invasion assays incorporating spheroid co-cultures embedded in matrigel.


 

HCT116 Uninhibited Cell Migration
Watch The Video
HT-1080 Uninhibited Wound Healing
cell-migration-invasion
Scratch Assay Starter Kit
Scratch Assay Starter Kit

 

 

Application Notes:

 

Visual Abstracts:

BioTek’s Visual Abstracts are brief animated presentations describing the Augmented Microscopy workflow of a specific application.

Cell Migration Assay: 3D Bioprinting Visual Abstract
Cell Migration Assay: 3D Bioprinting

Label-Free Tumor Invasion
Label-Free Tumor Invasion Assay
Using 3D Tumor Spheroids

Label-Free Tumor Invasion
Automated Wound Creation for Scratch Wound Healing Assays

 

Related Webinars:

 

Related Products:

Learn more about Cell Migration/Invasion applications - search our Application Notes and technical documentation in Resources.

 

Get more info

 

link