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  Vollautomatisierte Cell Imager
  
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  Multi-Plate Live Cell Imaging System
  
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  Synergy Neo2 Multi-Detektions-Reader mit Hybrid-Technologie
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  Synergy HTX Multi-Detektions-Reader
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  Mikroplatten-Reader
  
  Epoch 2 Mikroplatten-Spektralphotometer
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  ELx808 Mikroplatten-Reader für Absorptionsmessungen
  800 TS Mikroplatten-Reader für Absorptionsmessungen
  Peripheriegeräte
  
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  LogPhase 600 Microbiology Reader
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- Automation
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  BioSpa 8 Vollautomatisierter Inkubator
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- Software
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  Gen5 Datenanalyse-Software
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  Click here to find which microplate best fits your needs.
- Technologien
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Peripheriegeräte
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Applikationen
- Cell Culture QC
  
  Automated imaging tools can provide valuable information for improving routine cell culturing techniques and increasing the effectiveness and reproducibility of downstream cell-based assays. Conventional methods for evaluating cell culturing techniques and assay design consist of manual inspection of a small subset of the cell population at random locations and time points.
- Cell Health and Viability
  
  Cell health and viability measurements provide essential insight into a broad range of biological processes and treatment responses. Diverse assay formats and reagents have been developed that measure specific aspects of cell viability corresponding to particular cellular response pathways and mechanisms of injury.
- Cell Metabolism
  
  Cellular metabolism comprises a number of biochemical reactions that occur in concert within the cells of living organisms. These orchestrated reactions, better described as metabolic pathways allow organisms to function and respond to environmental changes. Agilent cell metabolism assays detect discrete changes in cell bioenergetics in real time, providing a window into the critical functions that provide ATP, the energy that cells need for activation, signaling, proliferation, and biosynthesis.
- Zellmigration und Invasion
  
  Cell migration and invasion are live cell kinetic assays useful in oncology research. The principle difference between migration and invasion is that migration refers to normal cell movement; whereas invasion describes cells actively invading surrounding tissue. It can do this under the influence of a chemoattractant gradient and secretion of proteases. There are numerous methods for performing these assays including scratch assays performed on a monolayer of cells adhered to plasticware (microplates or culture inserts) or using 3D cell culture models.
- Developmental Biology
  A macro trend in drug discovery is the use of complex models of disease early in preclinical studies. An approach following this viewpoint is the use of whole organism models involving living invertebrates and vertebrates such as nematodes and zebrafish conducive to drug screening methods.
- Histology and Slide Scanning
  Histology is typically performed on fixed tissue samples using upright microscopes equipped with oculars. Cytation™ and Lionheart™ FX provide automated digital imaging of these samples using color brightfield microscopy. Low to high magnifications from 1.25x to 60x (100x with Lionheart FX) can be combined with Cytation Gen5™ image processing features such as image stitching to increase field of view.
- Immunology
  The immune system relies on diverse mechanisms working in concert to defend the host from infection and to identify and remove aberrant or damaged cells. Dysregulation of the immune system can lead to a variety of disease conditions, including autoimmune disorders, allergies, and cancer. Additionally, the immune system is a critical consideration for vaccine development and cell, tissue and organ transplants.
- Immuno-Oncology
  While harnessing the patient’s immune system to fight cancer is not a new concept, there have been significant strides in the past decade to more effectively direct and activate components of the immune system and counter the measures certain tumors adopt to shield itself from immune attack. These include immunotherapeutic drugs based on directing immune cells to tumors based on specific antigens they present, PD-1 checkpoint inhibition and the ex vivo manipulation of the patient’s own immune cells to better drive an immune response to cancer.
- Mikrobiologie
  Since the advent of a lens system that enabled the visualization of bacteria and protists in 1671, the microscope remains a ubiquitous tool for the scientific study of live and fixed microorganisms. Investigating the structure, function, and typing of the highly diverse array of microorganisms spans heterogeneous applications including, but not limited to, the elucidation, diagnosis, and treatment of human and plant disease, food and water safety testing, vaccine development, investigation and production of industrial lipases, protein transfection to mammalian cells, environmental health and impact appraisal, horticultural and agricultural soil assessment, and exploration of alternative fuel sources.
- Molecular Biology and Biochemical
  Biochemical assays run the gamut from routine ELISAs to micro-volume nucleic acid and protein quantification. Endpoint and kinetic, single- and multi-wavelength assays are essential experimental tools. BioTek’s multi-mode readers have the flexibility to accommodate a very broad range of applications with superior performance.
- Rapid Cell Signaling
  G-protein coupled, seven-transmembrane (7-TM) receptors (GPCRs) represent large, diverse gene families found in fungi, plants and animals. The GPCR family of receptors is involved primarily with internalizing extracellular environmental signals via interaction with intracellular G-proteins. GPCR ligands and modulators range from peptide and non-peptide molecules to chemokines, nucleosides, growth factors and light.
- Stem Cell Research
  Research into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long term importance of this research resides in the use of stem cells for regenerative therapies; for the short term, however these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents.
- Virology
  Research into the diverse aspects of virology are made possible by a broad range of applications and assay formats, from relatively simple methods for viral detection to those designed to elucidate complex immune responses and pathological processes. BioTek instruments provide versatile platforms for conducting viral research, with optimized imaging- and plate reader-based solutions, as well as liquid handling and automation tools for increased assay throughput and reproducibility.
Quellen
- Gefragte Applikationen
  
  In BioTeks Applikationshinweisen finden Sie die aktuellsten wissenschaftlichen Inhalte bezogen auf die Anwendungsmöglichkeiten unserer gesamten Produktpalette. Suchen Sie nach Themen, Detektionsmethoden und Produkten oder nutzen Sie einfach unsere Stichwortsuche, um hilfreiche Applikationshinweise zu erhalten.
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- Literatur
  
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Technische Unterstützung
- Vertriebsbüros
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- Field Applications Scientists
  BioTek Field Applications Scientists (FAS) and Product Specialists provide unparalleled scientific support, assisting with experimental planning and assay optimization on BioTek’s instrumentation and software.
- Technische Unterstützung
  The BioTek Global Technical Support Center (GTS) is your Help Desk for all questions related to BioTek product use, maintenance, troubleshooting support and other frequently asked questions. Normal GTS hours are weekdays from 8:30 A.M. - 5:30 P.M Eastern Standard Time, excluding holidays.
- Weltweiter Service
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Über uns
- News
  Synergy H1’s Continuously Variable Bandwidth Monochromators Optimize Assay Performance
  July 2, 2020 - BioTek Instruments announces the availability of variable bandwidth monochromators on their modular and versatile Synergy™ H1 Hybrid Multi-Mode Reader. This allows researchers to achieve even greater levels of assay sensitivity and specificity compared to fixed bandwidth systems. Weiterlesen
  
  LogPhase 600 Microbiology Reader Measures Microbial Growth Curves in Multiple Microplates
  June 9, 2020 - BioTek unveils a unique class of microplate readers with the new LogPhase 600 Microbiology Reader. The LogPhase 600 is the only four-plate microplate reader purpose-built to perform microbial growth curve analysis. Multiple plate measurements increase throughput and reduce the need for multiple costly single-plate absorbance readers that take up valuable bench space. At the same time, highly consistent environmental conditions support high quality absorbance results without growth curve artifacts, even in bacterial and yeast assays with extended incubation periods. Weiterlesen
  
  Agilent’s BenchCel Microplate Handler Now Available through BioTek for Full Workflow Automation
  May 28, 2020 - BioTek announces that Agilent’s BenchCel Microplate Handler is now added to its portfolio of walkaway automated solutions. The modular BenchCel Microplate Handler is a high-speed robot with an open, flexible and scalable format to bring efficiency to diverse applications such as ELISA, endpoint add-and-read assays and cell fix-stain-image processes. Weiterlesen
  Weitere News
- Veranstaltungen
  Fisher Activate Science 2020: University of Konstanz
  
  September 23, 2020
  
  University of Konstanz
  BioTek instrumentation will be on display by BioTek Germany.
  
  Konstanz
  Germany
  
  Fisher Activate Science 2020: HIPRA Farma
  
  September 30, 2020
  
  HIPRA farma
  BioTek instrumentation will be on display by BioTek Europe.
  
  Amer
  Spain
  
  Fisher Activate Science 2020: Babraham Institute
  
  October 1, 2020
  
  Babraham Institute
  BioTek instrumentation will be on display by BioTek U.K.
  
  Babraham
  United Kingdom
  
  Weitere Veranstaltungen
- Customer Spotlights
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- Unsere Geschichte
  At BioTek we feel passionately and genuinely that our employees are our greatest asset. We continue to build our already impressive team having doubled our global workforce in the last five years. With our headquarters in the beautiful Green Mountains of Vermont, USA, we also have regional offices around the world.
  
  If you're interested in becoming part of our amazing team, check out our list of job openings today!
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- Karriere
  At BioTek we feel passionately and genuinely that our employees are our greatest asset. We continue to build our already impressive team having doubled our global workforce in the last five years. With our headquarters in the beautiful Green Mountains of Vermont, USA, we also have regional offices around the world.
  
  If you're interested in becoming part of our amazing team, check out our list of job openings today!
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Quellen - Graphische Präsentationen

Measuring Extracellular Oxygen Consumption Using a Soluble Fluorescent Biosensor

Related Products: Cytation 1 Multi-Detektions-Reader für Cell Imaging , Cytation 5 Multi-Detektions-Reader für Cell Imaging , Synergy H1 Multi-Detektions-Reader , Synergy Neo2 Multi-Detektions-Reader mit Hybrid-Technologie

May 20, 2020

Oxygen consumption is a metric that can be used to evaluate effects of different treatments on normal cellular respiration. One way to measure oxygen consumption is to detect how much oxygen in a cellular microenvironment is expended over time. This is indicated by an increasing signal from the Agilent MitoXpress Xtra Oxygen Consumption Assay biosensor shown here.

link

September 23, 2020

University of Konstanz

September 30, 2020

HIPRA farma

October 1, 2020

Babraham Institute

Quellen - Graphische Präsentationen

Measuring Extracellular Oxygen Consumption Using a Soluble Fluorescent Biosensor

Related Products: Cytation 1 Multi-Detektions-Reader für Cell Imaging , Cytation 5 Multi-Detektions-Reader für Cell Imaging , Synergy H1 Multi-Detektions-Reader , Synergy Neo2 Multi-Detektions-Reader mit Hybrid-Technologie