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February 16, 2018
Related Application: Live Cell Imaging
Macrophages are specialized cells that consume and digest foreign matter through phagocytosis. pH-sensitive bioparticles are a useful tool to study phagocytosis as particles fluorescence in response to the acidic environment of phagolysosomes. Cellular actin enables unique physical changes necessary for phagocytosis. This assay analyzed effects of actin disruption on bioparticle phagocytosis.